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Table 2 Average test scores (± standard deviation) obtained by the different models in the protein hold out use case (UC2). The suffix +emb indicates that protein sequence embeddings were concatenated to the I/O features. Best results are boldfaced

From: Sensitivity analysis on protein-protein interaction networks through deep graph networks

Model

MCC

F1

ACC

AUROC

Null

\(.000{\scriptstyle \pm .000}\)

\(.000{\scriptstyle \pm .000}\)

\(.680{\scriptstyle \pm .024}\)

\(.500{\scriptstyle \pm .000}\)

DeepSets

\(.021\scriptstyle \pm .036\)

\(.218\scriptstyle \pm .200\)

\(.572\scriptstyle \pm .169\)

\(.560\scriptstyle \pm .142\)

DeepSets+emb

\(.415\scriptstyle \pm .031\)

\(.605\scriptstyle \pm .038\)

\(.741\scriptstyle \pm .013\)

\(.783\scriptstyle \pm .033\)

DGN

\(.404\scriptstyle \pm .077\)

\(.604\scriptstyle \pm .043\)

\(.728\scriptstyle \pm .052\)

\(.791\scriptstyle \pm .038\)

DGN+emb

\(\mathbf {.512\scriptstyle \pm .040}\)

\(\mathbf {.667\scriptstyle \pm .032}\)

\(\mathbf {.788\scriptstyle \pm .019}\)

\(\mathbf {.844\scriptstyle \pm .025}\)