M3S-GRPred: a novel ensemble learning approach for the interpretable prediction of glucocorticoid receptor antagonists using a multi-step stacking strategy

Table 3 Performance of new feature representations over the ten-fold cross-validation and independent tests

Evaluation strategy	Feature	ACC	BACC	SN	SP	MCC	AUC
Cross-validation	PFV	0.900	0.903	0.908	0.898	0.713	0.965
	PFV_FS	0.898	0.900	0.903	0.897	0.708	0.964
Independent test	PFV	0.862	0.882	0.913	0.851	0.643	0.944
	PFV_FS	0.867	0.891	0.928	0.854	0.658	0.953

ISSN: 1471-2105