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Table 3 Comparison of Independent test results to all baseline methods

From: PathNetDRP: a novel biomarker discovery framework using pathway and protein–protein interaction networks for immune checkpoint inhibitor response prediction

  

AUCROC

 

Biomarker

Auslander

Prat

Riaz

Huang

Ours

PathNetDRP

0.779 ± 0.023

0.701 ± 0.009

0.655 ± 0.016

0.893 ± 0.023

SOTA

IMPRES

0.523 ± 0.026

0.661 ± 0.015

0.690 ± 0.005

0.312 ± 0.017

TIDE

0.421 ± 0.017

0.601 ± 0.063

0.525 ± 0.011

0.600 ± 0.031

NetBio

\(\underline{0.729 \pm 0.005}\)

\(\underline{0.699 \pm 0.003}\)

\(\underline{0.671 \pm 0.004}\)

0.747 ± 0.014

DeepGeneX

0.534 ± 0.032

0.614 ± 0.022

0.612 ± 0.019

\(\underline{0.885 \pm 0.023}\)

IRNet

0.696 ± 0.097

0.564 ± 0.039

0.584 ± 0.026

–

  1. \(^{\dagger }\)The ’bold’ and ’underline’ represent the best score and the 2nd score, respectively
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BMC Bioinformatics

ISSN: 1471-2105

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