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Fig. 2 | BMC Bioinformatics

Fig. 2

From: PathNetDRP: a novel biomarker discovery framework using pathway and protein–protein interaction networks for immune checkpoint inhibitor response prediction

Fig. 2

Overview of the Three Key Processes in PathNetDRP: A Application of the PageRank algorithm on the interaction network to identify the top 2000 genes closely associated with ICI targets. B Identification of biological pathways significantly associated with the selected 2000 gene candidates. C Configuration of subnetworks for each identified pathway and calculation of PathNetGene scores, quantifying the relevance of each gene within the context of its pathway

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BMC Bioinformatics

ISSN: 1471-2105

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