Fig. 3

DTreePred result screens. A Overall result, presenting DTreePred displayed as ‘N’ (neutral) or ‘P’ (pathogenic), and the number of classical predictors (NDamage) and ML algorithms (Machine Learning Score) that predict a pathogenic variant. If the variant is present in ClinVar, it is also displayed. B Advanced search screen to customize the query results. The user can filter the results by prediction scores, gene list, or final prediction. C Results from each of the 21 classical predictors. D Results from each of the 15 ML algorithms