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Table 2 ChIPbinner identifies differentially bound regions in broad histone marks with greater precision than csaw

From: ChIPbinner: an R package for analyzing broad histone marks binned in uniform windows from ChIP-Seq or CUT&RUN/TAG data

Histone mark

Metric

ChIPbinner

csaw

H3K36me2

Precision

1.00

0.670

Specificity

1.00

0.906

Sensitivity

0.998

0.998

F1 score

0.999

0.801

H3K4me1

Precision

1.00

0.688

Specificity

1.00

0.932

Sensitivity

0.923

0.998

F1 score

0.960

0.815

H3K27me3

Precision

1.00

0.957

Specificity

1.00

0.995

Sensitivity

0.961

0.961

F1 score

0.980

0.960

H3K9me3

Precision

1.00

1.00

Specificity

1.00

1.00

Sensitivity

0.958

0.962

F1 score

0.978

0.981