Table 1 The criteria for RS assignment
From: Uncovering latent biological function associations through gene set embeddings
Reliability score | Descriptions |
|---|---|
5 (Strong evidence) | The association is strongly supported by multiple independent studies and extensive literature evidence, showing clear biological relevance |
4 (Reported, with inference) | The association has been reported in the literature, but its biological relevance requires some level of inference or additional interpretation |
3 (Weak association) | The association has limited evidence in the literature, often mentioned in less direct contexts or without detailed mechanistic support |
2 (Speculative) | The association lacks direct literature evidence but is suggested by indirect data or weak connections |
1 (Minimal overlap) | The association is based on minimal overlap between gene sets or datasets, suggesting a tenuous link that is mostly speculative |
0 (No association) | The association is deemed biologically implausible, such as involving genes located on different chromosomes without known interactions |