Fig. 9
Hierarchical cluster analysis of different types of A0A and A0B demonstrating the capacity of the TSR algorithm for distinguishing their 3D structural differences. Panel a, the hierarchical cluster analysis showing 3D structural relationships of A0A and A0A. The numbers of A0A and A0B are labeled; panel b, the structural similarity between A0A—A0A pairs, A0B—A0B pairs and A0A—A0B pairs. The average similarity values, SDs, and 25/75 percentiles are indicated; panel c, the Venn diagram showing the numbers of TSR keys exclusively belonging to the A0A group, the A0B group and the intersection between the A0A group and the A0B group; panel d, the distinct, total, distinct common (C_Distinct), total common (C_Total), distinct specific (S_Distinct) and total specific (S_Total) TSR keys for A0A and A0B. The average values and SDs are indicated; panels e and f, the A0 common TSR key (6,966,113). The triangle corresponding to the key 6,966,113 for A0A (e) is constructed from the three Cα atoms from PsaB-W579, PsaA-F677 and PsaA-F687. The triangle corresponding to the key 6,966,113 for A0B (f) is constructed from the three Cα atoms from PsaA-F596, PsaB-F658 and PsaB-W668. The PDB is 5OY0