Table 4 Performances achieved by hub proteins
Methods | Tesnor | Hub proteins | ||||||
|---|---|---|---|---|---|---|---|---|
| Â | BioGRID | DIP | BioGRID | DIP | ||||
Order | 2nd | 3rd | 2nd | 3rd | 6th | Top 200 | Top 200 | Top 50 |
# of proteins | 195 | 475 | 195 | 55 | 38 | 199 | 179 | 45 |
# of genes | 217 | 503 | 193 | 57 | 41 | 229 | 190 | 59 |
Jensen Diseases | \(\bigcirc\) | 6 | \(\bigcirc\) | \(\bigcirc\) | \(\bigcirc\) | \(\bigcirc\) | \(\bigcirc\) | \(\bigcirc\) |
OMIM Disease | 2 | 3 | 9 | 9 | \(\bigcirc\) | 4 | \(\bigcirc\) | 6 |
LINCS L1000 Chem Pert Consensus Sigs | \(\bigcirc\) | \(\bigcirc\) | \(\bigcirc\) | 0 | 6 | \(\bigcirc\) | \(\bigcirc\) | 0 |
DSigDB | \(\bigcirc\) | \(\bigcirc\) | \(\bigcirc\) | \(\bigcirc\) | \(\bigcirc\) | \(\bigcirc\) | \(\bigcirc\) | \(\bigcirc\) |
DrugMatrix | \(\bigcirc\) | \(\bigcirc\) | 6 | 0 | 0 | \(\bigcirc\) | 0 | 1 |
Drug Perturbations from GEO down | \(\bigcirc\) | \(\bigcirc\) | \(\bigcirc\) | \(\bigcirc\) | \(\bigcirc\) | \(\bigcirc\) | \(\bigcirc\) | \(\bigcirc\) |
Drug Perturbations from GEO up | \(\bigcirc\) | \(\bigcirc\) | \(\bigcirc\) | \(\bigcirc\) | \(\bigcirc\) | \(\bigcirc\) | \(\bigcirc\) | \(\bigcirc\) |