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Table 2 To compare \(\langle n_{ii'1} \rangle _i\) between the selected and not selected proteins when using various \(u_{\ell _1 i}\) to select proteins, P-values were computed using the t test based on the alternative hypothesis that the mean \(\langle n_{ii'1} \rangle _i\) of the selected proteins was larger that that of not selected proteins

From: Novel artificial intelligence-based identification of drug-gene-disease interaction using protein-protein interaction

\(u_{\ell _1 i}\)s used

\(u_{2i}\)

\(u_{3i}\)

\(u_{6i}\)

 

Selected

Not selected

Selected

Not selected

Selected

Not selected

BioGRID

Mean \(\langle n_{ii'1} \rangle _i\)

\(3.63 \times 10^{-2}\)

\(1.84 \times 10^{-3}\)

\(1.97 \times 10^{-2}\)

\(1.78 \times 10^{-3}\)

—

—

P-value

\(5.32 \times 10^{-37}\)

\(2.53 \times 10^{-59}\)

—

DIP

Mean \(\langle n_{ii'1} \rangle _i\)

\(1.12 \times 10^{-3}\)

\(4.17 \times 10^{-4}\)

\(3.12 \times 10^{-3}\)

\(4.13 \times 10^{-4}\)

\(2.14 \times 10^{-3}\)

\(4.26 \times 10^{-4}\)

P-value

\(2.4 \times 10^{-4}\)

\(5.3 \times 10^{-5}\)

\(2.04 \times 10^{-13}\)