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Table 1 Performances of various protein selection methods for DIP

From: Novel artificial intelligence-based identification of drug-gene-disease interaction using protein-protein interaction

Methods

Tensor

multi-level

edge-betweenness

Order

2nd

3rd

1st

2nd

1st

2nd

# of proteins

195

55

144

138

39

82

# of genes

193

57

128

164

30

111

Jensen Diseases

\(\bigcirc\)

\(\bigcirc\)

\(\bigcirc\)

\(\bigcirc\)

7

5

OMIM Disease

9

9

8

0

0

0

LINCS L1000 Chem Pert Consensus Sigs

\(\bigcirc\)

0

4

1

0

\(\bigcirc\)

DSigDB

\(\bigcirc\)

\(\bigcirc\)

\(\bigcirc\)

\(\bigcirc\)

0

\(\bigcirc\)

DrugMatrix

6

0

0

0

0

0

Drug Perturbations from GEO down

\(\bigcirc\)

\(\bigcirc\)

0

0

0

2

Drug Perturbations from GEO up

\(\bigcirc\)

\(\bigcirc\)

6

0

1

0

  1. \(\bigcirc\)s denotes cases with more than or equal to 10 drugs associated with adjusted P-values less than 0.05. Otherwise, the corresponding practical numbers are presented