Fig. 4
Analysis of mouse cerebral cortex tissue using Spall. A Left: Image of the mouse brain tissue slice. Right: Pie plots representing the cell type composition at each spot, decomposed by Spall. B Spatial distribution of six layer-specific neuron populations predicted by Spall. C Comparison of spatial domain identification based on cell type proportions inferred by Spall versus direct use of gene expression profiles. D Left: Differential gene expression analysis of domains identified by Spall. Right: Top 5 differentially expressed genes in domain 14