Table 5 The corresponding p values of significant SNPs of AFC in the analysis of COPDGene using different imputation methods
Chr:bp\(^{1}\) | SNP\(^{2}\) | Unimputed | PHENIX | PIM | C-MSE | C-(0–1) | C-QL |
|---|---|---|---|---|---|---|---|
4:145431497 | rs1512282 | \(1.1\times 10^{-8}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) |
4:145434744 | rs1032297 | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) |
4:145474473 | rs1489759 | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) |
4:145485738 | rs1980057 | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) |
4:145485915 | rs7655625 | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) |
15:78882925 | rs16969968 | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) |
15:78894339 | rs1051730 | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) |
15:78898723 | rs12914385 | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) |
15:78911181 | rs8040868 | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) |
15:78878541 | rs951266 | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) |
15:78806023 | rs8034191 | \(1.40\times 10^{-8}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) |
15:78851615 | rs2036527 | \(2.90\times 10^{-8}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) |
15:78826180 | rs931794 | \(6.30\times 10^{-8}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) |
15:78740964 | rs2568494 | \(5.00\times 10^{-6}\) | \(5.00\times 10^{-7}\) | \(8.00\times 10^{-7}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) | \(\mathbf {<1.00E{-16}}\) |