Fig. 4

Evaluation of DrugMAN based on the drug structure similarity network and the protein sequence similarity network. DrugMAN with only the drug structure similarity network and the protein sequence similarity network as input (DrugMANSTR) outperforms three state-of-the-art chemoinformatic models but underperforms DrugMAN. The box plots show the median as the center lines and the mean as green triangles. The minima and lower percentile represent the worst and second-worst scores. The maxima and upper percentile indicate the best and second-best scores