Fig. 1
From: GPCR-BSD: a database of binding sites of human G-protein coupled receptors under diverse states
Comparison of muscarinic acetylcholine receptor M2 receptor structure in active (PDB: 4MQT) and inactive (PDB:Â 5YC8) states: a shifting in TM6 backbones; b orthosteric and allosteric binding sites in the active state; c orthosteric and allosteric binding sites in the inactive state; d shifting of the orthosteric binding pocket residues and surfaces e shifting of the allosteric binding pocket surfaces, f pocket width of the allosteric binding site measured in the active state, g pocket width of the allosteric binding site measured in the inactive state