Fig. 2
From: Translation regulation by RNA stem-loops can reduce gene expression noise
Fractional protein noise reduction by the mRNA inactivation loop as function of protein decay and mRNA activation rate constants. The colour of the heat map gives the protein noise (the squared coefficient of variation) in the two-stage model extended by the mRNA inactivation loop relative to the protein noise in a baseline two-stage model without the mRNA inactivation loop (adjusting the mRNA decay rate to obtain the same species means). The mRNA mean is set to \(\langle M \rangle = 10\), and protein mean is \(\langle P \rangle = 500\). The mRNA decay rate is set to \(\gamma _1^m = 1\) without loss of generality; the inactive mRNA decay rate is either the same as that of active mRNA (\(\gamma _2^m =1\); left panel) or set to zero (\(\gamma _2^m = 0\); right panel). The inactivation rate constant is \(q_{12} =3\)