Table 2 Enrichment analysis of stable lncRNA regulatory modules related to ASD
From: Modelling cell type-specific lncRNA regulatory network in autism with Cycle
Module ID | Terms | Description | p value | Ref. |
|---|---|---|---|---|
1 | R-HSA-8980692 | RHOA GTPase Cycle | 4.04E−02 | [55] |
2 | C0086132 | Depressive Symptoms | 3.85E−02 | [66] |
2 | GO:0005874 | microtubule | 2.35E−02 | [67] |
3 | C0242966 | Systemic Inflammatory Response Syndrome | 4.14E−02 | [47] |
3 | C0270549 | Generalized Anxiety Disorder | 3.40E−02 | [68] |
4 | GO:0007266 | Rho protein signal transduction | 4.98E−02 | [55] |
4 | GO:0030177 | positive regulation of Wnt signaling pathway | 4.98E−02 | [56] |
5 | C1300682 | Acute and chronic colitis | 3.93E−02 | [69] |
5 | R-HSA-196854 | Metabolism of vitamins and cofactors | 4.15E−02 | [70] |
6 | GO:0014003 | oligodendrocyte development | 1.67E−04 | [71] |
6 | GO:0061564 | axon development | 5.53E−03 | [72] |
6 | C0598589 | Inherited neuropathies | 1.71E−02 | [73] |
6 | GO:0007215 | glutamate receptor signaling pathway | 2.09E−02 | [74] |
7 | GO:0005112 | Notch binding | 4.46E−02 | [58] |
8 | GO:0000723 | telomere maintenance | 2.52E−02 | [75] |
9 | GO:0043401 | steroid hormone mediated signaling pathway | 2.93E−02 | [76] |
10 | GO:0007422 | peripheral nervous system development | 3.14E−02 | [48] |
10 | GO:0032292 | peripheral nervous system axon ensheathment | 3.14E−02 | [48] |
10 | R-HSA-9012999 | RHO GTPase Cycle | 4.12E−02 | [55] |
11 | GO:0007163 | establishment or maintenance of cell polarity | 2.46E−02 | [77] |