Fig. 3

Mouse Embryo Usage over Theiler stage heatmaps for central nervous system genes. Each heatmap is subdivided on the y-axis by strain and Theiler stage. The darker the blue, the higher the usage. Panel A shows all strains have the least GC content in the second codon position. There is a strong preference for dinucleotide AG (Panel B) and junction dinucleotide CA (Panel C) for all strains. Codon usages are similar across all strains, leading with GAG (Gln) and AAG (Arg) (Panel D). Panel E describes the codon pair usage (scaled) for all synonymous Alanine:Alanine (AlaAla) and Alanine:Arginine (AlaArg) codon pairs, revealing very little variation in usage across strains than any other type of usage