A comparative analysis of mutual information methods for pairwise relationship detection in metagenomic data

Francis, Dallace; Sun, Fengzhu

doi:10.1186/s12859-024-05883-7

BMC Bioinformatics

Table 1 Areas under the ROC curves (AUCs) for each metric under exploitative, commensal, and amensal relationships

From: A comparative analysis of mutual information methods for pairwise relationship detection in metagenomic data

		Log normal	Exponential	Negative binomial	Gamma	Beta negative binomial	Avg
Exploitative	MINE	0.941 ± 0.028	0.936 ± 0.025	0.731 ± 0.059	0.884 ± 0.041	0.826 ± 0.050	0.864
	NWJ	0.925 ± 0.032	0.879 ± 0.040	0.745 ± 0.057	0.856 ± 0.044	0.738 ± 0.058	0.823
	DOE	0.800 ± 0.050	0.772 ± 0.057	0.727 ± 0.062	0.691 ± 0.062	0.721 ± 0.060	0.742
	MIC	0.823 ± 0.051	0.724 ± 0.059	0.663 ± 0.062	0.656 ± 0.062	0.606 ± 0.064	0.694
	KSG (5)	0.917 ± 0.033	0.866 ± 0.041	0.699 ± 0.062	0.804 ± 0.051	0.700 ± 0.066	0.797
	LNC (7)	0.901 ± 0.033	0.865 ± 0.042	0.723 ± 0.058	0.874 ± 0.040	0.700 ± 0.059	0.813
	Partitioning (3)	0.781 ± 0.055	0.786 ± 0.053	0.677 ± 0.062	0.739 ± 0.058	0.720 ± 0.057	0.741
Commensal	MINE	0.971 ± 0.017	0.966 ± 0.021	0.900 ± 0.038	0.974 ± 0.015	0.922 ± 0.031	0.946
	NWJ	0.886 ± 0.044	0.879 ± 0.043	0.820 ± 0.056	0.913 ± 0.036	0.773 ± 0.056	0.854
	DOE	0.921 ± 0.031	0.943 ± 0.024	0.925 ± 0.029	0.933 ± 0.027	0.933 ± 0.028	0.931
	MIC	0.895 ± 0.035	0.871 ± 0.041	0.868 ± 0.039	0.861 ± 0.042	0.806 ± 0.051	0.860
	KSG (9)	0.945 ± 0.024	0.959 ± 0.022	0.905 ± 0.034	0.927 ± 0.030	0.937 ± 0.025	0.935
	LNC (9)	0.955 ± 0.025	0.977 ± 0.012	0.884 ± 0.036	0.919 ± 0.031	0.948 ± 0.022	0.937
	Partitioning (5)	0.902 ± 0.035	0.897 ± 0.035	0.838 ± 0.049	0.894 ± 0.037	0.846 ± 0.046	0.875
Amensal	MINE	0.833 ± 0.048	0.760 ± 0.054	0.800 ± 0.051	0.824 ± 0.046	0.831 ± 0.049	0.801
	NWJ	0.842 ± 0.044	0.840 ± 0.047	0.854 ± 0.043	0.870 ± 0.044	0.854 ± 0.043	0.852
	DOE	0.678 ± 0.060	0.732 ± 0.059	0.731 ± 0.058	0.679 ± 0.062	0.772 ± 0.054	0.718
	MIC	0.798 ± 0.050	0.691 ± 0.064	0.723 ± 0.058	0.726 ± 0.057	0.717 ± 0.059	0.731
	KSG (5)	0.815 ± 0.048	0.729 ± 0.059	0.726 ± 0.057	0.787 ± 0.050	0.770 ± 0.055	0.765
	LNC (7)	0.763 ± 0.052	0.705 ± 0.061	0.820 ± 0.050	0.756 ± 0.056	0.749 ± 0.056	0.759
	Partitioning (3)	0.467 ± 0.066	0.543 ± 0.070	0.708 ± 0.058	0.616 ± 0.062	0.719 ± 0.057	0.611

Best results for each prior distribution by relationship type are indicated by bolded font

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ISSN: 1471-2105

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