Table 8 Enrichment results for the p53 mutation dataset in a single experiment
From: Ant colony optimization for the identification of dysregulated gene subnetworks from expression data
| Â | Proposed method | GeneSurrounder | LEAN | limma | |
|---|---|---|---|---|---|
Total # of significant pathways | 60 | 110 | 83 | 46 | |
KEGG Pathway ID | KEGG Pathway Name | Ranking (p value) | |||
hsa04115 | p53 signaling pathway | 2 (1.86e−09) | 4 (9.32e−09) | 3 (9.31e−14) | 5 (3.49e−10) |
hsa04110 | Cell cycle | 1 (5.47e−19) | 1 (1.39e−20) | 23 (1.99e−05) | NA (0.61) |
hsa04210 | Apoptosis | 5 (1.73e−05) | 86 (0.01) | 9 (3.09e−10) | 28 (6.54e−06) |
hsa04218 | Cellular senescence | 7 (3.30e−05) | 26 (1.06e−04) | 15 (5.86e−08) | NA (0.61) |