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Table 1 Summary of VCF file handling tools and their capabilities

From: VCF observer: a user-friendly software tool for preliminary VCF file analysis and comparison

 

Comparison

GUI

Filtering

Benchmarking

Visualization

Metadata

VCFtools

×

 

×

   

BCFtools

×

 

×

   

BrowseVCF

 

×

×

   

VCF-miner

 

×

×

   

VIVA

  

×

 

×

×

123VCF

 

×

×

   

VCF observer

×

×

×

×

×

×

  1. Features present in various tools for handling VCF files are marked with a cross. Only command line tools allow the comparison of VCF files while they do not provide visualization capabilities. Filtering capabilities offered by VCF-Miner, BrowseVCF, and 123VCF allow the use of custom annotations while the others do not