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Table 2 Performance comparison with other HRD prediction tools on the TCGA-OV and GDC data sets

From: expHRD: an individualized, transcriptome-based prediction model for homologous recombination deficiency assessment in cancer

 

Cohort

Sensitivity

Specificity

Accuracy

Precision

F-score

AUC-ROC

AUC-PR

MCC

expHRD

TCGA

0.7105

0.95

0.7931

0.9643

0.8182

0.7988

0.33

0.6283

Guang Peng et al.

0.4737

0.85

0.6034

0.8571

0.6102

0.6583

0.272

0.3201

expHRD

GDC

0.9054

0.5526

0.7857

0.7976

0.8481

0.7738

0.6099

0.5008

Guang Peng et al.

0.5405

0.6579

0.5804

0.7547

0.6299

0.5892

0.4087

0.1882