Fig. 3

Validation of expHRD performance in the TCGA-OV test set. a Pearson’s correlation between expHRD and scarHRD in the TCGA-OV test set (n = 58, PCC = 0.768, p = 2.045e−12). The blue line denotes the regression line, while the shaded area represents the 95% confidence interval (CI). b Receiver operating characteristic (ROC) curve plotting sensitivity against 1-specificity values for expHRD score’s capacity to predict scarHRD-high instances within TCGA-OV test samples. c, d Kaplan–Meier overall survival analysis contrasting patients with high vs. low scarHRD (c) or expHRD (d) status within the TCGA-OV test set. P-values obtained via the log-rank test