Fig. 5
From: A guided network estimation approach using multi-omic information

Fructose (a) and Glucose-6-phosphate (b) do not have similar QTLs and therefore do not share an edge in \({\varvec{W}}(\hat{{\varvec{Y}}}^{M}({\varvec{X}}^S))\). The \(-\log _{10}\) p-value score for every marker is plotted when CIM is used. The red dotted vertical lines are plotted as a visual separation between the 5 chromosomes and the chromosome number is indicated on the x-axis below each segment. The dotted horizontal blue line marks the \(-\log _{10}\) p-value score of 3. Red dots on the x-axis are placed on marker positions for which NCR estimated non-zero coefficients. The color transparency indicates the magnitude of the regularized estimated coefficient. The correspondence between CIM and NCR can be seen by noticing that red dots on the x-axis are in most areas where the \(-\log _{10}\) p-value score has high values