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Fig. 7 | BMC Bioinformatics

Fig. 7

From: Using sensitivity analyses to understand bistable system behavior

Fig. 7

Arc length and parameter perturbation at the population level. Maximum arc length ratio vs. percentage change in parameter value for a population of 20, 000 models. Each setting for a given parameter draws from a log-normal distribution with \(3\sigma \) equal to the percent change. This generates an output distribution of arc length ratios, the maximum of which is considered. The parameter cluster \(\{k_1,k_2\}\) causes transition to the monostable state the earliest when compared to \(\{k_3, k_4\}\). Lower panel shows a zoomed-in view of the upper panel capturing the instances where perturbation in each parameter achieves bifurcation

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