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Fig. 5 | BMC Bioinformatics

Fig. 5

From: Using sensitivity analyses to understand bistable system behavior

Fig. 5

Arc length measure in parameter-state space. The parameter-state space consists of the perturbed parameter (one at a time) and the concentrations of the participating species. The bifurcation curve shown is in this space. Initial ON state corresponds to the nominal system model (\(s=0\)). After a non-zero perturbation along the \(k-\)axis, the system moves by an arc length \(s=D\). When further perturbed, the system is eventually pushed to the bifurcation point (\(s=s_{off}\)) where it transitions to a monostable system at the bifurcation point labeled OFF

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