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Fig. 4 | BMC Bioinformatics

Fig. 4

From: Systematic interrogation of mutation groupings reveals divergent downstream expression programs within key cancer genes

Fig. 4

GATA3 downstream effects can be decomposed into two orthogonal axes. Amongst the divergent subgroupings enumerated for GATA3 in our breast cancer cohorts, we found a pair of non-overlapping subgroupings that produced mutation scores with no correlation with one another in both METABRIC(LumA) and TCGA-BRCA(LumA). Each cohort sample is represented by a point, with samples shaded according to whether they carried a mutation in one of the subgroupings, neither, or in both as indicated by the figure labels and legend

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BMC Bioinformatics

ISSN: 1471-2105

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