Fig. 9
From: NemoProfile as an efficient approach to network motif analysis with instance collection

Process to predict essential proteins in a PPI network. A PPI network is processed to obtain NemoProfile matrix (A) that shows protein i has A ij overlaps with motif j. The matrix is directly loaded into a Weka program to run a decision tree algorithm and is evaluated through 10-fold cross-validation method to provide prediction rate and ROC area value as a result