Fig. 5
From: Contextualization of drug-mediator relations using evidence networks
a Condition-specific dependency network (CDN) for BRD-8899 for drug-sensitive cell lines. Dashed lines represent statistical dependencies while solid lines represent known interactions. Size of nodes represents node essentiality. b CDN for BRD-8899 for drug-insensitive cell lines. c Evidence network for the BRD-8899 – BRCA2 drug-mediator pair. All edges represent a known association based from the STRING/STITCH databases. Blue edges represent mediator-gene associations. Red edges represent drug-gene associations