Fig. 1
From: Assessment of transfer methods for comparative genomics of regulatory networks in bacteria
Comparison of methods for the evaluation of TRN transfer. The plots show the histogram of Euclidean distance, KL divergence, ROC-AUC and PR-AUC values for simulated bidirectional transfers between 179 TF-specific species pairs using different degrees of noise (10, 25, 50 and 75 % of random sites sampled when creating pseudo-replicates), as well as their random and permuted controls. The y-axis shows the number of transfers within each binning value on the x-axis. ROC-AUC and PR-AUC values are normalized to the respective AUC of the known target TF-binding motif to compensate for the decreased search efficiency of low information content motifs