Protein disulfide topology determination through the fusion of mass spectrometric analysis and sequence-based prediction using Dempster-Shafer theory

Table 5 Known and determined S-S bonds for all molecules by combining MS2DB+, SVM, and CSP using the Shafer rule.

Protein	Known Bonds	Bonds Found	Belief
ST8Sia IV	142-292, 156-356	142-292, 156-356	0.66, 0.68
Beta-LG	82-176, 122-135	82-176, 122-135	0.49, 0.36
FucT VII	68-76, 211-214, 318-321	68-76, 211-214, 318-321	0.43, 0.26, 0.54
Β1,4-GalT	134-176, 247-266	134-176, 247-266	0.35, 0.36
C2GnT-I	59-413, 100-172, 151-199, 372-381	59-413, 100-172, 151-199, 372-381	0.07, 0.08, 0.26,0.06
Lysozyme	24-145, 48-133	24-145, 48-133, 82-98, 94-112	0.31, 0.13, 0.10, 0.10
FT III	81-338, 91-341	81-338	0.67

ISSN: 1471-2105