Table 3 More # of non-H, # of non-H polar bonds and # of rotatable bonds could increase the potency of HIV Protease Inhibitors.
From: Multi-target QSAR modelling in the analysis and design of HIV-HCV co-inhibitors: an in-silico study
Precursor | Structure | pKi | |
|---|---|---|---|
#17 pKi: 9.28 |
|
| + 2.11% (× 25.3) |
#17 pKi: 9.28 |
|
| + 2.04% (× 25.3) |
#17 pKi: 9.28 |
|
| + 1.95% (× 25.2) |
